Do omega-3s meaningfully improve cognition or protect the brain?

“there's been several trials, to show that omega-3 fatty acids are most beneficial and most effective for mild cognitive impairment patients. People who have the ApoE4 gene and people who have got Alzheimer's disease.”

“Omega-3s by far. One of the most potent stimulus that you could have for the brain. They help with cell membrane fluidity. ... Another thing that they do is they are comparable to an NSAID, an anti-inflammatory medication. These have massive anti-inflammatory effects. In fact, I think that these have the safety profile of an FDA-approved drug. And there's only”

“all of our transporters, all of Our receptors, right? They're embedded in the cell membrane. And the fluidity of that membrane is important for the structure and function of these things. And that's why omega-3 affects dopamine, serotonin”

“The data is all going to come from observational trials for the most part. ... and they seem to be positive. ... if you look at all the observational data, just like we did with the statins, where it's in general pretty good, I think if you went through all of that data with omega-3s in the brain, you would”

“omega-3s. Okay. These are so well established in the literature. They reduce inflammation. They help with cognition. Something like two to four grams a day.”

“I believe that everybody needs to bump up their omega-3, specifically DHA consumption. So always been and remains On the top of my list, in terms of do I make a global supplement recommendation, if I had to choose one, not sure if that's what your question was, but I would say DHA.”

“an interesting study published about two months ago challenged the wisdom that omega-3 supplements, fish oil in particular, was good for the brain. ... And concluded that fish oil was of no benefit in reducing risk of Alzheimer's, and in fact, may have actually slightly increased risk.”

“It was originally shown in the VITACOG trial that was run out of the University of Oxford. It was then replicated in the BPROOF trial. Then the other side has also been shown. There was a, in the omega-AD trial, they showed that supplements with omega-3s didn't result in any benefit if people had elevated homocysteine.”

“it's probably better for Alzheimer's, right? If someone's starting to show signs of Alzheimer's, I think it's better for, yeah, for that, the data. I think the problem is universally supplementing is not necessarily the way to go. You want to find a deficit and then supplement, right?”

“there are now at least three randomized controlled trials that have shown that omega-3 status and B vitamin status interact, and they're dependent on one another.”

“all of our transporters, all of Our receptors, right? They're embedded in the cell membrane. And the fluidity of that membrane is important for the structure and function of these things. And that's why omega-3 affects dopamine, serotonin”

“there are now at least three randomized controlled trials that have shown that omega-3 status and B vitamin status interact, and they're dependent on one another.”

“The data is all going to come from observational trials for the most part. ... and they seem to be positive. ... if you look at all the observational data, just like we did with the statins, where it's in general pretty good, I think if you went through all of that data with omega-3s in the brain, you would”

“all of our transporters, all of Our receptors, right? They're embedded in the cell membrane. And the fluidity of that membrane is important for the structure and function of these things. And that's why omega-3 affects dopamine, serotonin”

“The data is all going to come from observational trials for the most part. ... and they seem to be positive. ... if you look at all the observational data, just like we did with the statins, where it's in general pretty good, I think if you went through all of that data with omega-3s in the brain, you would”

“there are now at least three randomized controlled trials that have shown that omega-3 status and B vitamin status interact, and they're dependent on one another.”